Physiological basis for lithokinetic therapy


DOI: https://dx.doi.org/10.18565/nephrology.2019.3.63-69

V.V. Dutov, D.M. Popov, A.A. Podoynitsyn, A.A. Rumyantsev, S.Yu. Buymistr, V.I. Bondarenko, V.S. Goncharuk, M.T.S. Dadashov

1) M.F. Vladimirsky Moscow Regional Research and Clinical Institute; Moscow, Russia 2) Zhukovsky City Clinical Hospital; Moscow region, Russia
The conservative treatment of ureteral stones remains one of the problems in the treatment of urolithiasis. Despite the development and improvement of medical instruments and methods for surgical removal of stones, the use of conservative effect aimed at ensuring the spontaneous passage of stones and their fragments from the upper urinary tract (UUT) has not lost its significance.
The desire to accelerate the process of stone discharge led to the widespread occurrence of a variety of physiotherapeutic procedures. With the accumulation of knowledge about the molecular biochemical characteristics of the physiology of smooth muscle cells of the ureter and the development of pharmacological science, there is growing interest in the possibility of targeted use of medications, the effect of which could significantly accelerate the process of spontaneous stone discharge.
Keywords: urolithiasis, upper urinary tract, ureter function
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About the Autors

Valery V. Dutov – Doctor of Medical Sciences, Professor, Head of the Department of Urology FCME, Chief Researcher at the M.F. Vladimirsky Moscow Regional Research and Clinical Institute; Moscow, Russia. E-mail: valeriy.dutov.52@mail.ru, tel. +7 (495) 681-09-15;
Dmitry M. Popov – PhD in Medical Sciences, Doctor of the Urology Unit of the Zhukovsky City Clinical Hospital; Moscow, Russia. E-mail: surgeon67@yandex.ru,
Tel. +7 (926) 319-37-79
Andrey A. Rumyantsev –PhD in Medical Sciences, Head of the Urology Unit, Associate Professor at the Department of Urology of the FCME, M.F. Vladimirsky Moscow Regional Research and Clinical Institute; Moscow, Russia. E-mail: rumyancevuro@mail.ru
Aleksey A. Podoynitsyn – PhD in Medical Sciences, Teaching Assistant at the Department of Urology of the FCME, Deputy Chief Physician of the M.F. Vladimirsky Moscow Regional Research and Clinical Institute; Moscow, Russia. E-mail: a9251252261@gmail.com
Svetlana Yu. Buymistr – Postgraduate Student at the Department of Urology, M.F. Vladimirsky Moscow Regional Research and Clinical Institute; Moscow, Russia.
E-mail: svetlanabuymistr@mail.ru
Vyacheslav I. Bondarenko – Postgraduate Student at the Department of Urology, M.F. Vladimirsky Moscow Regional Research and Clinical Institute; Moscow, Russia.
E-mail: iprists@gmail.com
Vitaliy S. Goncharuk – Postgraduate Student at the Department of Urology, M.F. Vladimirsky Moscow Regional Research and Clinical Institute; Moscow, Russia.
E-mail: goncharuk.vitalii@inbox.ru. Tel. +7 (926) 363-75-89.
Magamed Tagi S. Dadashov – Resident Physician at the Department of Urology of the FCME, M.F. Vladimirsky Moscow Regional Research and Clinical Institute; Moscow, Russia. E-mail: tagidadashov@gmail.com, Tel. +7 (926)170-57-97.

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