The evolution of ideas about the kidney functions and their role in the regulation of water and mineral metabolism


DOI: https://dx.doi.org/10.18565/nephrology.2024.2.83-92

Koroshchenko G.A., Subotyalova A.M., Aizman R.I., Subotyalov M.A.

1) Novosibirsk State Pedagogical University, Department of Anatomy, Physiology and Life Safety, Novosibirsk, Russia; 2) Novosibirsk National Research State University, Department of Fundamental Medicine, Novosibirsk, Russia; 3) Novosibirsk Scientific Research Institute of Hygiene, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Novosibirsk, Russia
The article presents the prerequisites, formation and development of ideas about the physiology of the kidneys and salt and water metabolism.
Objective. Analysis of the basic ideas about kidney function, starting from the era of the Ancient world and ending with studies of the modern period.
Material and methods. When preparing the text of this publication, articles in publications included in the RSCI and PubMed were used. The depth of the search for publications was 20 years, and a number of earlier works relevant to the research topic were also included in the review.
Results. The results on the process of formation and development of ideas about the physiology of the kidneys are presented. In the Ancient World and the Middle Ages, scientists identified the urinary function of the kidneys as the main one. In modern age, the mechanisms of kidney function began to be studied. In modern times, the morphofunctional and molecular foundations of kidney physiology have been largely studied in foreign laboratories; the role of the kidney as a homeostatic organ that regulates the balance of water and ions under the influence of neurohumoral factors has been comprehensively studied mainly by domestic authors.

About the Autors


Galina A. Koroshchenko – Cand.Sci.(Biol.), Associate Professor at the Department of Anatomy, Phys-iology and Life Safety, Novosibirsk State Pedagogical University. Address: 28 Vilyuiskaya at., Novosi-birsk, 630126; e-mail: svyatashg@mail.ru.
Anna M. Subotyalova – Student in the Master's Programmу at the Department of Anatomy, Physi-ology and Life Safety, Novosibirsk State Pedagogical University. Address: 28 Vilyuiskaya at., Novosi-birsk, 630126; e-mail: anyuta108@mail.ru.
Roman I. Aizman – Dr.Sci. (Biol.), Professor of the Department of Anatomy, Physiology and Life Safety, Novosibirsk State Pedagogical University. Address: 28 Vilyuiskaya at., Novosibirsk, 630126; e-mail: aizman.roman@yandex.ru.
Mikhail A. Subotyalov – Dr.Sci. (Med.), Professor at the Department of Anatomy, Physiology and Life Safety, Novosibirsk State Pedagogical University. Address: 28 Vilyuiskaya at., Novosibirsk, 630126; Associate Professor at the Department of Fundamental Medicine, Novosibirsk National Research State University. Address: 1 Pirogov st., Novosibirsk, 630090; e-mail: subotyalov@yandex.ru


Similar Articles


Бионика Медиа