Objective. Creation of a unified register of renal biopsies of the Kyrgyz Republic (RBKR). Establishment of relationship between morphological and clinical manifestations of glomerulopathy.
Material and methods. The study included 245 patients who underwent a study of renal tissue samples obtained in vivo by percutaneous biopsy from 2015 to 2019. All patients underwent a complex of general clinical, biochemical, immunological, instrumental and morphological studies.
Results. In the pediatric cohort, 41 (41.8%) patients with hematuria combined with nephrotic proteinuria were followed-up, and it was the maximum number of all examined children. Patients with nephritic and nephrotic syndromes were detected with the same frequency in 27 (27.5%) and 22 (22.4%) patients, respectively. Isolated urinary syndrome was detected only in 8 (8.16%) patients. In the adult cohort, nephritic-range proteinuria was more often recorded – in 96 (65.3%) patients. Isolated urinary syndrome was observed in 30 (20.4%) patients. It should be emphasized that the incidence of all clinical manifestations (proteinuria with and without hematuria) compared with children differed.
Conclusion. The most common variants of glomerular lesion in adults includrd membranous glomerulonephritis (MN [38%]) and immunoglobulin A nephropathy (IgAN; 29.2%), whereas in children IgAN and the minimal change glomerulonephritis dominated, in 20.4 and 19.3%, respectively.

Keywords: morbidity, renal biopsy, epidemiology, register