Evaluation of the effectiveness of screening for sarcopenia in hemodialysis patients


Yu.V. Lavrishcheva, A.A. Yakovenko, A.Sh. Rumyantsev, A.N. Belskikh

1) S.M. Kirov Military Medical Academy; Saint-Petersburg, Russia 2) Pavlov First St. Petersburg State Medical University; Saint-Petersburg, Russia 3) St. Petersburg State University; Saint-Petersburg, Russia
Objective. Evaluation of the effectiveness of SARC-F sarcopenia screening method in hemodialysis patients.
Material and methods. 317 patients who received treatment with program bicarbonate hemodialysis for 8.2±5.1 years were examined; there were 171 women and 146 men, the mean age was 57.1±11.3 years. Assessment of the presence of sarcopenia was performed using the method recommended by EWGSOP (European Working Group on Sarcopenia in Older People). The SARC-F method was used for sarcopenia screening.
Results. When diagnosing sarcopenia according to the EWGSOP recommendations, the SARC-F method showed an accuracy index for the diagnosis of sarcopenia at the level of 53%, i.e. the probability of error was almost equal to the probability of setting the correct diagnosis. For the SARC-F screening method, the area under the ROC curve (AUC) did not exceed 0.57, which indicates the low predictive value of this method as a method for sarcopenia screening. If there is a risk of developing sarcopenia according to the SARC-F method, there is a significant decrease in the main laboratory parameters, anthropometric parameters, and body composition indicators compared with indicators of patients with a negative result of sarcopenia screening.
Conclusion. The use of the SARC-F sarcopenia screening method in hemodialysis patients is inappropriate due to its low predictive value.

About the Autors


Yulia V. Lavrishcheva – Nephrologist at the Almazov National Medical Research Center, Teaching Assistant at the Department of Nephrology and Efferent Therapy, S.M. Kirov Military Medical Academy; Saint-Petersburg, Russia. E-mail: lavrischeva@gmail.com, ORCID ID: 0000-0002-3073-2785.
Aleksandr A. Yakovenko – PhD in Medical Sciences, Associate Professor at the Department of Nephrology and Dialysis, Pavlova First St. Petersburg State Medical University; Saint-Petersburg, Russia. E-mail: leptin-rulit@mail.ru, ORCID ID: 0000-0003-1045-9336.
Aleksandr Sh. Rumyantsev – Doctor of Medical Sciences, Professor at the Department of Faculty Therapy, Faculty of Medicine, St. Petersburg State University; Saint-Petersburg, Russia. E-mail: rash.56@mail.ru, ORCID ID: 0000-0002-9455-1043.
Andrey N. Belskikh – Corresponding Member of RAS, Doctor of Medical Sciences, Professor at the Department of Nephrology and Efferent Therapy, S.M. Kirov Military Medical Academy; Saint-Petersburg, Russia.


Similar Articles


Бионика Медиа