Objective. A retrospective analysis of renal biopsy register data for 7 years.
Material and methods. A retrospective study on the results of 6387 biopsies of native kidneys performed from 2013 to 2020
at the Moscow State Scientific Center on the basis of City Clinical Hospital № 52 of the Moscow Healthcare Department.
Results. The most common indications for renal biopsy included isolated urinary syndrome and nephrotic syndrome (33.0 and 32.5% of cases), as well as newly diagnosed renal failure (27%). Less commonly, a biopsy was performed for acute nephritic syndrome (3.5%) and to clarify the morphological picture of an already diagnosed systemic disease (4%). In the structure of glomerular pathology, primary glomerulopathies were detected in 51% of patients, more than half (26%) of which were cases of IgA nephropathy. Membranous nephropathy, idiopathic FSGS and minimal change disease were detected less commonly (10.5%, 7.5% and 7%, respectively). Among secondary glomerulopathies, ANCA-associated vasculitis (7%) and SLE (5%) prevailed, also, lymphoproliferative diseases (3.6%), in most cases represented by AL-amyloidosis (2.5%); as well as kidney damage in diabetes mellitus (3.2%) and hereditary nephropathy (2.7%) were detected.
Conclusion. The data obtained are consistent with the prevalence of primary glomerulopathies in the structure of kidney pathology, such as IgA nephropathy, membranous nephropathy, FSGS and MCD; for rarer variants of kidney pathology, however, the results of the registries can vary significantly depending on the diagnostic criteria and indications for biopsy.

Keywords: tubulointerstitial changes, vascular pathology, glomerular diseases, kidney pathology, renal biopsy