The results of 5-year experience in testing the glomerular filtration rate by the INVITRO laboratory in the territory of the Russian Federation


DOI: https://dx.doi.org/10.18565/nephrology.2021.2.27-33

D.V. Fadin, V.A. Fedin, B.V. Zingerman, O.N., Kotenko, I.G. Kargalskaya

1) INVITRO Company, Moscow, Russia; 2) OOO «INVITRO», Moscow, Russia; 3) OOO TelePat, Moscow, Russia; 4) Moscow City Scientific and Practical Center for Nephrology and Kidney Transplant Pathology, City Clinical Hospital № 52 of the Moscow Healthcare Department, Moscow, Russia
Objective. Assessment of the distribution of test results for the estimated glomerular filtration rate by stages of CKD
(from 1 to 5 as renal function decreases), as well as assessment of the possibility of detecting of patients with a high stage of asymptomatic CKD at the initial screening.
Materials and methods: 77,719 tests were analyzed for the period 01.12.2014 - 28.10.2020. For the analysis, data selected from the unified INVITRO database and completely (irreversibly) depersonalized were used.
Results: More than half of the remaining results (63,920 tests) were abnormal (GFR <90). Over 5 years of follow-up, the number of such patients was 32,235 (50.5%), 6866 (10.8%) cases of serious deviations (CKD stage 3-5). The dynamics of GFR testing showed a gradual increase in the number of tests starting at the end of 2014 (when this test began to carried out in INVITRO) from 0 to 500 tests per month taken from corporate clients and 1000 tests per month taken from patients without referral. The prevalence of CKD stage 3–5 among adults was 2.7%. In October 2018, a significantly lower percentage of identified CKD stage 3-5 and a significantly higher percentage of normal GFR values were recorded. These results were obtained during a publicity campaign, and active educational work in the media, including central television and popular high-circulation magazines during the period of 2018.

About the Autors


D.V. Fadin – Director for Strategic Development and Innovation, INVITRO Group, Moscow, Russia
V.A. Fedin – General Director, OOO "INVITRO - Information Technologies", Moscow, Russia
B.V. Zingerman – Scientific Director of OOO TelePat LLC, Moscow, Russia
O.N. Kotenko – Cand. Sci. (Med.), Chief External Expert in Nephrology of the Moscow Healthcare Department, Head of the Moscow City Scientific and Practical Center for Nephrology and Kidney Transplant Pathology, City Clinical Hospital № 52 of the Moscow Healthcare Department, Moscow, Russia
I. G. Kargalskaya – Head of the Patient-Oriented Telemedicine Committee at the All-Russian Union of Patients, Moscow, Russia


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