The results of 5-year experience in testing the glomerular filtration rate by the INVITRO laboratory in the territory of the Russian Federation
D.V. Fadin, V.A. Fedin, B.V. Zingerman, O.N., Kotenko, I.G. Kargalskaya
1) INVITRO Company, Moscow, Russia;
2) OOO «INVITRO», Moscow, Russia;
3) OOO TelePat, Moscow, Russia;
4) Moscow City Scientific and Practical Center for Nephrology and Kidney Transplant Pathology, City Clinical Hospital № 52 of the Moscow Healthcare Department, Moscow, Russia
Objective. Assessment of the distribution of test results for the estimated glomerular filtration rate by stages of CKD
(from 1 to 5 as renal function decreases), as well as assessment of the possibility of detecting of patients with a high stage of asymptomatic CKD at the initial screening.
Materials and methods: 77,719 tests were analyzed for the period 01.12.2014 - 28.10.2020. For the analysis, data selected from the unified INVITRO database and completely (irreversibly) depersonalized were used.
Results: More than half of the remaining results (63,920 tests) were abnormal (GFR <90). Over 5 years of follow-up, the number of such patients was 32,235 (50.5%), 6866 (10.8%) cases of serious deviations (CKD stage 3-5). The dynamics of GFR testing showed a gradual increase in the number of tests starting at the end of 2014 (when this test began to carried out in INVITRO) from 0 to 500 tests per month taken from corporate clients and 1000 tests per month taken from patients without referral. The prevalence of CKD stage 3–5 among adults was 2.7%. In October 2018, a significantly lower percentage of identified CKD stage 3-5 and a significantly higher percentage of normal GFR values were recorded. These results were obtained during a publicity campaign, and active educational work in the media, including central television and popular high-circulation magazines during the period of 2018.
About the Autors
D.V. Fadin – Director for Strategic Development and Innovation, INVITRO Group, Moscow, Russia
V.A. Fedin – General Director, OOO "INVITRO - Information Technologies", Moscow, Russia
B.V. Zingerman – Scientific Director of OOO TelePat LLC, Moscow, Russia
O.N. Kotenko – Cand. Sci. (Med.), Chief External Expert in Nephrology of the Moscow Healthcare Department, Head of the Moscow City Scientific and Practical Center for Nephrology and Kidney Transplant Pathology, City Clinical Hospital № 52 of the Moscow Healthcare Department, Moscow, Russia
I. G. Kargalskaya – Head of the Patient-Oriented Telemedicine Committee at the All-Russian Union of Patients, Moscow, Russia