Features of the course of aa-amyloidosis in rheumatoid arthritis against the background of COVID-19 infection


DOI: https://dx.doi.org/10.18565/nephrology.2021.2.72-75

E.V. Voloshinova, N.M. Nikitina, N. D. Smirnova, E.V. Egorova

Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia
Rheumatoid arthritis (RA) is currently one of the most common causes of AA amyloidosis; and the renal damage is associated with the severity of systemic inflammation. Severe chronic infections can also lead to the development and progression of AA amyloidosis, and acute infections can worsen the course of AA amyloidosis. The evaluation of the features of the course of AA amyloidosis against the background of a new coronavirus infection is of undoubted interest. The article presents authors’ own clinical observation of the development of nephrotic syndrome against the background of SARS-CoV-2 in a patient with seropositive RA and morphologically confirmed AA-amyloidosis.
Keywords: SARS-CoV-2, anti-inflammatory therapy, rheumatoid arthritis, nephrotic syndrome, amyloidosis
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About the Autors

Elena V. Voloshinova – Cand. Sci. (Med.), Associate Professor at the Department of Hospital Therapy, Faculty of General Medicine, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia; e-mail: voloshinovaelena@mail.ru, ORCID ID: 0000-0002-6883-0567.
Natalya M. Nikitina – Dr. Sci. (Med.), Professor at the Department of Hospital Therapy, Faculty of General Medicine, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia; e-mail: e-mail: nikina02@yandex.ru, ORCID ID: 0000-0002-0313-119
Natalya D. Smirnova – Resident at the Department of Hospital Therapy, Faculty of General Medicine, Saratov State Medical University n.a. V.I.Razumovsky, Saratov, Russia; e-mail: e-mail: syrrax@yandex.ru, ORCID ID: 0000-0001-8847-9017
Ekaterina V. Egorova – Postgraduate Student at the Department of Hospital Therapy, Faculty of General Medicine, Saratov State Medical University n.a. V.I.Razumovsky, Saratov, Russia; e-mail: kapustik@mail.ru, ORCID ID: 0000-0003-2818-115X


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