Growing albuminuria was considered to be a marker of early stages of hypertonic and diabetic nephropathy for a long time. Now days it has the meaning of the integral marker of unfavorable prognosis. Its forecasting role is very important due to the fact that it reflects the generalized endothelial dysfunction, determining the injury of target organs (myocardium, vascular wall, kidney). This damage is well observed even for insignificant increase of albumin excretion. A lot of therapeutic strategies, applied to decrease cardiovascular risk and kidney injury, can reduce albuminuria, but the most effective one includes the use of angiotensin-converting enzyme inhibitors and angiotensin II receptors blockers.

Keywords: cardiovascular events, сhronic kidney disease, albuminuria, prognosis