Left ventricular diastolic function in nephrogenic arterial hypertension in patients with preserved renal function


N.Yu. Borovkova, N.N. Borovkov, L.A. Biriukova, E.O. Obukhova, Yu.A. Khorkina, A.I. Arshinova

¹Nizhny Novgorod State Medical Academy; ²N.A. Semashko Nizhny Novgorod Regional Clinical Hospital. Nizhny Novgorod, Russia
Aim. Assessment of diastolic function of left ventricle (LV) in hypertensive patients with chronic glomerulonephritis and preserved renal function.
Methods. 136 hypertensive patients with chronic glomerulonephritis and preserved renal function were included into the study. Doppler-echocardiography was preformed in all patients.
Results. E/A ratio in hypertensive patients with chronic glomerulonephritis was significantly higher, than in healthy controls. Time of isovolumetric relaxing increased according to the arterial hypertension stage, while time of delay of early diastolic filling decreased.
Conclusion. Hypertensive patients with chronic glomerulonephritis and preserved kidney function have diastolic dysfunction of left ventricle, which progresses according to the acceleration of arterial hypertension.

About the Autors


Borovkova N. Yu. – hospital therapy department assistant professor at Nizhny Novgorod State Medical Academy, Ph.D.
E-mail: borovkov-nn@mail.ru;
Borovkov N. N., - hospital therapy department head, professor at Nizhny Novgorod State Medical Academy, Ph.D.;
Burikova L.A. - ultrasonic medical investigation specialist at ultrasonic medical investigation department of N.A. Semashko Nizhny Novgorod Regional Clinical Hospital. Nizhny Novgorod, Russia;
Obukhova E. O. - hospital therapy department assistant professor at Nizhny Novgorod State Medical Academy, functional diagnostics department head of N.A. Semashko Nizhny Novgorod Regional Clinical Hospital. Nizhny Novgorod, Russia, Ph.D.;
Khor’kina Yu.A. – Ph.D. student at hospital therapy department at Nizhny Novgorod State Medical Academy;
Arshinova A. I.- ultrasonic medical investigation specialist at ultrasonic medical investigation department of N.A. Semashko Nizhny Novgorod Regional Clinical Hospital. Nizhny Novgorod, Russia


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