Clinical significance of asymptomatic bacteriuria in patients with chronic heart failure


G.P. Arutiunov, A.G. Arutiunov, D.D. Pashkevich, N.Yu. Voevodina, N.O. Balanina, M.I. Korsunskaya, A.V. Grishina

1 Pirogov Russian National Research Medical University Ministry of Health and Social Development of Russian Federation, Moscow
Aim. Study of frequence and prognostic significance of asymptomatic bacteriuria in decompensated chronic heart failure (CHF).
Methods. 116 patients with acute decompensation of CHF were inluded into the study. In all of them bacteriology of the urine was performed in first 48 hours after hospitalisation, as well as in days 10 and 30. Frequency of hospitalisations and mortality were assessed during 12 months.
Results. Asymptomatic bacteriuria was revealed in 25,9% of patients. Patients with asymptomatic bacteriuria had more prominent symptoms of CHF decompensation. Antibacterial therapy of asymptomatic bacteriuria in CHF patients had temporal effect. Patients with CHF class III – IV (NYHA) and asymptomatic bacteriuria were hospitalised more frequently. Presence of asymptomatic bacteriuria was associated with elevation of frequency of hospitalisations and combined endpoint – hosptitalisation and/or death.
Conclusion. Asymptomatic bacteriuria is associated with unfavorable clinical outcome in CHF.

About the Autors


Arutynov G.P. – professor, head of the therapeutic department of Pediatric Faculty of Pirogov Russian National Research Medical University Ministry of Health and Social Development of Russian Federation, Ph.D.
Arutiunov A.G. – Assistant of therapeutic department of Pediatric Faculty of Pirogov Russian National Research Medical University Ministry of Health and Social Development of Russian Federation, Ph.D.
Pashkevich D.D. – Ph.D. Student of the therapeutic department of Pediatric Faculty of Pirogov Russian National Research Medical University Ministry of Health and Social Development of Russian Federation.
E-mail: daria_pashkevich@mail.ru;
Voevodina N.Yu. – vice-head physician on medical division of State Budgetary Healthcare Institution City Clinical Hospital #4 Department of Healthcare of Moscow, Ph.D.;
Balanina N.O. – head of clinical-diagnosis laboratory at State Budgetary Healthcare Institution City Clinical Hospital #4 Department of Healthcare of Moscow;
Korsunskaya M.I. – head of 19th therapeutic department at State Budgetary Healthcare Institution City Clinical Hospital #4 Department of Healthcare of Moscow, Ph.D.;
Grishina A.V. - head of 26th therapeutic department at State Budgetary Healthcare Institution City Clinical Hospital #4 Department of Healthcare of Moscow, Ph.D.


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