Combined positron-emission tomographyand computed tomography scanning of the kidneys and urinary tract


DOI: https://dx.doi.org/10.18565/nephrology.2019.1.28-31

V.B. Berdichevsky, B.A. Berdichevsky, V.A. Zhmurov, D.A. Barashin, F.R. Rasulov, A.V. Romanova, I.V. Pavlova, E.V. Zagorchik

Nephrourological Clinic of Tyumen State Medical University; Tyumen, Russia
Background. Combined positron-emission tomography and computed tomography (PET/CT) allows to investigate the functional state of organs and systems in real time in vivo. The basis of the method includes the principle of incorporation of an isotope of vital biomolecules into the structure of actively multiplying or vigorously functioning cells.
Objective. Evaluation of the possibility of analyzing the structural and functional state of the kidneys and urinary tract according to the results of PET/CT whole body scanning of patients with skin melanoma and prostate cancer without signs of metastasis and the presence of neuro-urological anamnesis.
Material and methods. A retrospective analysis of 100 PET/CT findings of patients in these groups was carried out. In 50 cases, the scanning was conducted with the choline C 11, and in 50 cases – with the fludeoxyglucose F 18. PET/CT was performed by the standard method on a PET/CT scanner (Siemens Biograph, Germany) to assess the possible prevalence of the disease.
Results. The obtained data allowed to conclude that PET/CT imaging of functionally consistent kidneys and urinary tract is possible and rather highly informative. Mathematical calculation of the intensity of radiopharmaceutical agent incorporation into the renal cortex, renal medulla, as well as the renal pelvis, makes it possible to evaluate the functional state of the renal parenchyma in the process of urine formation and urinary tract in the process of urine transport, and also to perform it separately for each organ.
Conclusion. Structural and functional changes in the parenchyma of the kidneys and the upper urinary tract during the formation and transportation of urine can be visually and mathematically analyzed using the combined PET/CT method.

About the Autors


Berdichevsky V.B. – Doctor of Medical Sciences, Associate Professor at the Department of Oncology with a Course of Urology of the Tyumen State Medical University; Tyumen, Russia. E-mail: neurourofcn@mail.ru
Berdichevsky B.A. – Doctor of Medical Sciences, Professor at the Department of Oncology with a Course of Urology at the Tyumen State Medical University; Tyumen, Russia.
D.A. Barashin – External Doctorate Student at the Clinical Department of Propaedeutics of Internal Diseases of Tyumen State Medical University of the Ministry of Health of the Russian Federation, Radiologist at the Radiological Center of the Tyumen Regional Oncology Dispensary (SAHCI TR MDCMC Medical City, Tyumen) of the Ministry of Health of the Russian Federation; Tyumen, Russia.
Zhmurov V.A. – Doctor of Medical Sciences, Professor, Head of the Clinical Department of Propedeutics of Internal Diseases, Tyumen State Medical University; Tyumen, Russia.
Romanova A.V. – Medical Resident at the Clinical Department of Internal Medicine Propedeutics, Tyumen State Medical University of the Ministry of Health of the Russian Federation; Tyumen, Russia.
Rasulov F.R. – External Doctorate Student at the Clinical Department of Propedeutics of Internal Diseases, Tyumen State Medical University of the Ministry of Health of the Russian Federation; Tyumen, Russia.
Pavlova I.V. – External Doctorate Student at the Clinical Department of Propedeutics of Internal Diseases, Tyumen State Medical University of the Ministry of Health of the Russian Federation; Tyumen, Russia.
Zagorchik E.V. – 6th-year Student of the Medical Faculty of the Tyumen State Medical University; Tyumen, Russia.


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