The possibilities of therapeutic intervention and prevention of cerebrovascular complications in atrial fibrillation in patients on program hemodialysis


DOI: https://dx.doi.org/10.18565/nephrology.2019.3.54-62

I.T. Murkamilov, I.S. Sabirov, V.V. Fomin, K.A. Aitbaev, F.A. Yusupov, N.A. Regzhapova, A.Sh. Sarybaev, B.Zh. Imanov, G.U. Asymbekova, A.A. Ibragimov, A.B. Mamytova, B.D. Isakov, M.I. Isaeva, F.K. Baysymakova, A.Sh. Kurumshieva, B.S. Sarymsakova, Z.A. Aidarov

1) I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan; Bishkek, Kyrgyzstan 2) Kyrgyz-Russian Slavic University n.a. the First President of Russia B.N. Yeltsin, Bishkek, Kyrgyzstan 3) Sechenov First Moscow State Medical University; Moscow, Russia 4) Scientific Research Institute of Molecular Biology and Medicine at the National Center for Cardiology and Therapy of the Ministry of Health of the Kyrgyz Republic; Bishkek, Kyrgyzstan 5) Osh State University; Osh, Kyrgyzstan 6) National Center for Cardiology and Therapy named after Acad. Mirsaid Mirrahimov at the Ministry of Health of the Kyrgyz Republic; Bishkek, Kyrgyzstan 7) Bishkek Research Center for Traumatology and Orthopedics; Bishkek, Kyrgyzstan 8) Medical Center “Nephro Doctor”; Bishkek, Kyrgyzstan 9) Republican Diagnostic Center; Bishkek, Kyrgyzstan 10) National Hospital of the Ministry of Health of the Kyrgyz Republic; Bishkek, Kyrgyzstan
The article is devoted to the important interdisciplinary problem – atrial fibrillation (AF) and the risk of cerebrovascular complications (CVCs) in patients on program hemodialysis (PHD). Data on the prevalence of AF and its relationship with CVCs are presented, and clinical and pathogenetic variants of AF in patients with 5D stage of chronic kidney disease are discussed. The neurological aspects of AF in this category of patients and dosage regimens for anticoagulant therapy are considered.
Keywords: program hemodialysis, atrial fibrillation, cerebrovascular complications, stroke prevention, therapy with oral anticoagulants, acetylsalicylic acid, warfarin, rivaroxaban, apixaban
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About the Autors

Ilkhom T. Murkamilov – PhD in Medical Sciences, Nephrologist, Deputy Associate Professor at the Department of Faculty Therapy, I.K. Akhunbaev KSMA; Bishkek, Kyrgyzstan. E-mail: murkamilov.i@mail.ru, ORCID: 0000-0001-8513-9279
Ibragim S. Sabirov – Doctor of Medical Sciences, Professor, Head of the Department of Therapy № 2 in the specialty “Medical Care, Kyrgyz-Russian Slavic University n.a. the First President of Russia B.N. Yeltsin; Bishkek, Kyrgyzstan. E-mail: sabirov_is@mail.ru, ORCID: 0000-0002-8387-5800
Victor V. Fomin – Doctor of Medical Sciences, Professor, Corresponding Member of the Russian Academy of Sciences, Vice-Rector for Clinical Work and Postgraduate Professional Education, Director of the V.N. Vinogradov Faculty Therapy Clinic, Head of the Faculty Therapy Department № 1, Sechenov First MSMU; Moscow, Russia.
E-mail: fomin_vic@mail.ru, ID: 34769949900
Kuvanych A. Aitbaev – Doctor of Medical Sciences, Professor, Head of the Laboratory of Pathological Physiology, Research Institute of Molecular Biology and Medicine; Bishkek, Kyrgyzstan. E-mail: kaitbaev@yahoo.com
Furkat A.Yusupov – Doctor of Medical Sciences, Professor, Head of the Department of Neurology and Psychiatry, Faculty of Medicine, Osh State University; Osh, Kyrgyzstan. E-mail: furcat_y@mail.ru
Nodira A. Regzhapova – Postgraduate Student at the Department of Neurology and Psychiatry, Faculty of Medicine, Osh State University; Osh, Kyrgyzstan.
E-mail: nredzhapova@mail.ru:
Akpay Sh. Sarybaev – Doctor of Medical Sciences, Professor, Deputy General Director of the National Center for Cardiology and Therapy named after Academician Mirsaid Mirrakhimov under the Ministry of Health of the Kyrgyz Republic; Bishkek, Kyrgyzstan. E-mail: ak_sar777@mail.ru
Bakyt Zh. Imanov – PhD in Medical Sciences, Senior Researcher at the Department of Ultrasound Diagnostics, National Center of Cardiology and Therapy named after Academician Mirsaid Mirrahimov; Bishkek, Kyrgyzstan. E-mail: bimanov@mail.ru
Gulnara U. Asymbekova – Doctor of Medical Sciences, Professor, Department of Obstetrics and Gynecology, Kyrgyz-Russian Slavic University n.a. the First President of Russia B.N. Yeltsin; Bishkek, Kyrgyzstan. Email: ginak@krsu.edu.kg
Abdubakir A. Ibragimov – PhD in Medical Sciences, Therapist, Associate Professor at the Department of Faculty Therapy, I.K. Akhunbaev KSMA; Bishkek, Kyrgyzstan.
E-mail: top.sm2014@mail.ru
Anara B.Mamytova – Doctor of Medical Sciences, Professor, Head of the Department of Surgical Dentistry, Kyrgyz-Russian Slavic University n.a. the First President of Russia B.N. Yeltsin; Bishkek, Kyrgyzstan. E-mail: demilge@bk.ru
Bakyt D. Isakov – Doctor of Medical Sciences, Deputy Director for Organizational and Methodological Work, Bishkek Research Center for Traumatology and Orthopedics; Bishkek, Kyrgyzstan. E-mail: bakytr@mail.ru
Mira I. Isaeva – PhD in Medical Sciences, Nephrologist, Transplantologist, Associate Professor, Medical Center "Nephro Doctor"; Bishkek, Kyrgyzstan. E-mail: mira.isaeva@mail.ru
Farida K. Baysymakova – Nephrologist, Republican Diagnostic Center; Bishkek, Kyrgyzstan. E-mail: asatkulovich@mail.ru
Aparkul Sh. Kurumshieva – PhD in Medical Sciences, Nephrologist, Associate at the the Department of Hospital Therapy, Occupational Pathology with a Course of Hematology I.K. Akhunbaev KSMA; Bishkek, Kyrgyzstan. E-mail: kgma.gospter@mail.ru
Burma S. Sarymsakova – Nephrologist, National Hospital of the Ministry of Health of the Kyrgyz Republic; Bishkek, Kyrgyzstan. E-mail: body_fly@inbox.ru
Ziyabidin A. Aidarov – Doctor of Medical Sciences, Professor, Head of the Department of Public Health and Healthcare Service, I.K. Akhunbaev KSMA; Bishkek, Kyrgyzstan. E-mail: aydarov.ziabidin.65@mail.ru

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