Русский
Kidney condition in patients with spondyloarthritis receiving genetically engineered biologic drugs
DOI: https://dx.doi.org/10.18565/nephrology.2020.2.21-25
K.D. Dorogoykina, D.S. Sedov, K.A. Gamayunova, A.P. Rebrov
Saratov State Medical University named after V.I. Razumovsky; Saratov, Russia
Material and methods. An analysis of the disease activity and the kidney condition in 18 SpA patients who received GEBDs for
a year was performed.
Results. Against the background of the 1-year use of GEBDs, a significant decrease in glomerular filtration rate with a normal serum creatinine level was noted. The frequency of glucocorticoid administration has been reduced during the treatment with GEBDs. The importance of early diagnosis of kidney damage and the timely initiation of therapy with GEBDs in SpA patients has been demonstrated.
Conclusion. Timely prescribing of GEBDs in most cases allows achieving better control of the SpA activity and preventing or reducing the severity of developing complications, including kidney damage. Further evaluation of the GEBD effect of on renal function is required.
About the Autors
Ksenia D. Dorogoykina – Postgraduate Student at the Department of Hospital Therapy, Faculty of Medicine, Saratov State Medical University named after V.I. Razumovsky; Russia, Saratov. E-mail: dorogoykinakd@mail.ru; ORCID 0000-0003-1765-2737
Dmitry S. Sedov – Postgraduate Student at the Department of Hospital Therapy, Faculty of Medicine, Saratov State Medical University named after V.I. Razumovsky; Russia, Saratov. E-mail: 77sedov77@mail.ru; ORCID: 0000-0003-2260-0958
Kristina A. Gamayunova – Postgraduate Student at the Department of Hospital Therapy, Faculty of Medicine, Saratov State Medical University named after V.I. Razumovsky; Russia, Saratov. E-mail: k.a.gamayunova@mail.ru
Andrey P. Rebrov – Doctor of Medical Sciences, Professor, Head of the Department of Hospital Therapy, Faculty of Medicine, Saratov State Medical University named after
V.I. Razumovsky; Russia, Saratov. E-mail: andreyrebrov@yandex.ru; ORCID: 0000-0002-3463-7734
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