Русский
The functional state of the kidneys and albuminuria in individuals with cardiovascular risk factors
DOI: https://dx.doi.org/10.18565/nephrology.2022.1.27-32
Mikhailova L.V., Shupina M.I., Safonova V.S., Butova V.V., Sheremet V.V.
1) Immanuele Kant Baltic Federal University, Medical Institute, Kaliningrad, Russia; 2) OOO "Sanatorium "Yantarny Bereg", Svetlogorsk, Kaliningrad region, Russia
Material and methods: The cross-sectional study included 70 outpatients with cardiovascular risk factors, mean age 66 (60; 72) years. Traditional risk factors and the presence of concomitant diseases were assessed. The calculation of the glomerular filtration rate was carried out according to the CKD-EPI formula, the albuminuria level was determined by the urine albumin/creatinine ratio.
Results: It was revealed that 20 (29%) of the examined patients had signs of CKD C3, 33 (47%) had albuminuria level A2 and higher.
In the surveyed population, eGFR was associated with age (r=-0.51, P<0.05), and the level of albuminuria – with TG (r=0.31, P<0.05). In patients with abdominal obesity, the albuminuria level was statistically significantly higher, and eGFR did not depend on the presence of abdominal obesity.
Conclusion: In patients with abdominal obesity, the albuminuria level, rather than eGFR, is an important prognostic marker.
About the Autors
Larisa V. Mikhailova – Cand. Sci. (Med.), Associate Professor at the Department of Therapy, Medical Institute, Immanuele Kant Baltic Federal University.
Address: 4/6 Botkin st., Kaliningrad, Kaliningrad region, 236016; e-mail: mihalysa@mail.ru, ORCID 0000-0001-5070-5955
Marina I. Shupina – Cand. Sci. (Med.), Associate Professor at the Department of Therapy, Medical Institute, Immanuele Kant Baltic Federal University.
Address: 4/6 Botkin st., Kaliningrad, Kaliningrad region, 236016, e-mail: mshupina@mail.ru, ORCID 0000-0002-7653-2017
Vera S. Safonova – 5th year student of the Medical Institute, Immanuele Kant Baltic Federal University. Address: 4/6 Botkin st., Kaliningrad, Kaliningrad region, 236016;
e-mail: vsafonova099@gmail.com, ORCID 0000-0002-8707-8876
Viktoria V. Butova – 4th year student of the Institute of Living Systems, Immanuele Kant Baltic Federal University. Address: 4/6 Botkin st., Kaliningrad, Kaliningrad region, 236016; e-mail: VButova@stud.kantiana.ru, ORCID 0000-0002-4621-944
Vera V. Sheremet – Head of the CDL, OOO "Sanatorium "Yantarny Bereg". Address: 79A Kaliningradsky prospect, Svetlogorsk, Kaliningrad region, 238560.
ORCID 0000-0003-1557-0615
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