Analysis of functional results of surgical treatment of kidney cancer


DOI: https://dx.doi.org/10.18565/nephrology.2023.4.60-66

Popov S.V., Guseinov R.G., Yesayan A.M., Sivak K.V., Perepelitsa V.V., Sadovnikova A.V., Grushevsky R.O., Lelyavina T.A.

1) St. Petersburg St. Luke Clinical Hospital, St. Petersburg, Russia; 2) S. M. Kirov Military Medical Academy, St. Petersburg, Russia; 3) St. Petersburg State University, St. Petersburg, Russia; 4) Smorodintsev Research Institute of Influenza, St. Petersburg, Russia; 5) St. Petersburg Medical and Social Institute, St. Petersburg, Russia; 6) Almazov National Medical Research Center, St. Petersburg, Russia
Background. The result of surgical treatment of kidney cancer (KC) is determined not only by cancer-specific survival, but also by impaired renal function, which may occur in the patient as a concomitant pathology or develop after surgery, especially afterf radical nephrectomy. Timely diagnosis and prevention of renal dysfunction progression in patients with KC is an urgent task of modern onconephrology.
Objective. This literature review analyzes the functional results of surgical treatment of KC.
Material and methods. A review of published scientific literature in the Pubmed, Elsevier, Springer, and Elibrary databases for 2018–2023was conducted.
Results. A review of the scientific literature showed that patients with KC often have concomitant chronic kidney disease. In addition, malignant kidney tumors themselves are associated with an increased risk of nephropathies.
Conclusion. The use of organ-sparing operations for KC makes it possible to preserve renal function to a greater extent at the initial (preoperative) level, prevent the development or progression of existing renal dysfunction and improve the functional outcomes of treatment and the quality of life of patients.

About the Autors


Sergey V. Popov – Dr.Sci. (Med.), Professor, Chief Physician of St. Petersburg St. Luke Clinical Hospital, Head of the Center for Endoscopic Urology and New Technologies, Professor at the Department of Urology, S.M. Kirov Military Medical Academy, Head of the Department of Urology, St. Petersburg Medical and Social Institute. Address: 46 Chugunnaya st., St. Petersburg, Russia, 194044. Tel.: +7 (812) 576-11-08. E-mail: doc.popov@gmail.com. ORCID ID 0000-0003-2767-7153
Ruslan G.Guseynov – Cand.Sci. (Med.), Deputy Chief Physician for Scientific Activities, St. Petersburg St. Luke State Clinical Hospital, Teaching Assistant at the Department of Hospital Surgery, St. Petersburg State University. Address: 46 Chugunnaya st., St. Petersburg, Russia, 194044. Tel.: +7 (812) 576-11-08. E-mail: rusfa@yandex.ru. ORCID ID 0000-0001-9935-0243
Ashot M. Yesayan – Dr.Sci. (Med.), Professor, Head of the Department of Nephrology and Dialysis, Faculty of Postgraduate Education, Pavlov University, Chief External Expert in Nephrology of the Northwestern Federal District of the Russian Federation. Address: 17 Lev Tolstoy st., St. Petersburg, Russia, 197022. Tel.: +7 (812) 338-69-20. E-mail: essaian.ashot@gmail.com. ORCID: 0000-0002-7202-3151
Konstantin V.Sivak – Smorodintsev Research Institute of Influenza. Address: 15/17 Prof.Popov st., St. Petersburg, Russia, 197376. E-mail: lucaclinic.ru. ORCID: 0000-0003-4064-5033
Vitaly V.Perepelitsa – Cand. Sci. (Med.), Urologist, St. Petersburg St. Luke Clinical Hospital. Address: 46 Chugunnaya st., St. Petersburg, Russia, 194044. Tel.: +7 (812) 576-11-08. E-mail: perepelitsa_vit@mail.ru. ORCID iD 0000-0002-7656-4473
Anastasia V. Sadovnikova– Nephrologist, St. Petersburg St. Luke Clinical Hospital. Address: 46 Chugunnaya st., St. Petersburg, Russia, 194044 Tel.: +7 (812) 576-11-08. E-mail: stenia1407@mail.ru. ORCID ID 0009-0004-9544-7944
Roman O. Grushevsky – Nephrologist, St. Petersburg St. Luke Clinical Hospital. Address: 46 Chugunnaya st., St. Petersburg, Russia, 194044.. E-mail: lucaclinic.ru
Tatyana A. Lelyavina – Dr.Sci. (Med.), Leading Researcher at the Research Institute of Myocardial Microcirculation and Metabolism, Almazov National Medical Research Center. Address: lit. B2 15 Parkhomenko Ave.,St. Petersburg, E-mail: tatianalelyavina@mail.ru. https://orcid.org/0000-0002-1834-4982


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