Ожирение и заболевания почек: скрытые последствия эпидемии


К.П. Ковесди, С. Фурс, К. Зоккали

1 Отделение нефрологии медицинского факультета Научного центра здоровья Университета Теннесси; Мемфис, Теннесси, США 2 Отдел нефрологии Мемфисского медицинского центра ветеранов армии; Мемфис, Теннесси, США 3 Отделение педиатрии Медицинской школы Перельмана Университета Пенсильвании; Филадельфия, Пенсильвания, США 4 Отдел клинической эпидемиологии и патофизиологии заболеваний почек и гипертензии Центра научных исследований Института клинической физиологии; Калабрия, Италия
Ожирение стало всемирной эпидемией, и, по прогнозам, его распространенность в ближайшем десятилетии увеличится на 40%. Растущая распространенность ожирения оказывает влияние на риск развития сахарного диабета, сердечно-сосудистых заболеваний, а также хронической болезни почек (ХБП). Высокий индекс массы тела – один из наиболее значимых факторов риска ХБП. У лиц с ожирением в ответ на увеличение метаболических потребностей избыточной массы тела развивается компенсаторная гиперфильтрация. Увеличение внутриклубочкового давления может приводить к повреждению почек и повышению риска развития ХБП в отдаленном периоде.
В последние годы частота развития гломерулопатии, ассоциированной с ожирением, выросла в 10 раз. Кроме того, показано, что ожирение является фактором риска нефролитиаза и ряда злокачественных новообразований, в т.ч. рака почки. В этом году инициатива «Всемирный День почки» выдвигает образовательную программу, которая разъясняет опасные последствия ожирения и его связь с заболеваниями почек, пропагандирует здоровый образ жизни и мероприятия по его формированию как доступную основу профилактики неблагоприятных последствий ожирения.

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Об авторах / Для корреспонденции


Информация об авторах:
Всемирный День почки, Международное общество нефрологов в сотрудничестве с Международной федерацией почечных фондов,
Rues de Fabriques 1B, 1000, Brussels, Belgium.
E-mail: myriam@worldkidneyday.org


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