Growth retardation and body mass deficiency in children with chronic kidney disease stage II – V (Russian registry of children with chronic renal failure)


M.S. Molchanova, E.K. Petrosian, S.E. Kazymova, E.A. Molchanova

Aim. Study of characteristics of growth retardation and body weight deficiency development in children with chronic kidney disease (CKD) stage II - V. Methods. 960 children with CKD II - V from the Russian registry of children with chronic renal failure (2008) were analyzed. 834 children (519 boys, 315 girls) had CKD II-IV; 126 children (69 boys, 57 girls) had CKD V. Mean age of children was 11,6 ± 4,6 years (1 - 17,9 years). Body weight and height were assessed according to centile tables. Results. In children with CKD II-IV стадиями 37,0% and 32,4%, respectively, had their weight and height values below 3rd centile. Patients with renal cystic dysplasy, renal hypoplasy, obstructive uropathy, malignant tumors and tubulopathies demonstrated more prominent weight deficiency and growth retardation. Growth retardation severity depended on duration of the disease and renal replacement therapy. Conclusion. In children with CKD growth retardation and weight deficiency correlated with CKD progression and etiology of CKD.

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