Русский
Calcium and phosphorus metabolism in children with neurogenic urination disorders
DOI: https://dx.doi.org/10.18565/nephrology.2019.4.17-20
D.Yu. Latyshev, Yu.F. Lobanov, Ya.F. Zverev, N.A. Tekutyeva, N.M. Mikheeva
Altai State Medical University, Barnaul, Russia
Material and methods. The study included 25 children suffering from neurogenic urination disorders, mean age was 10.4±3.6 years. The blood vitamin D, calcium, phosphorus, osteocalcin and parathyroid hormone levels and urine deoxypyridinoline level were evaluated.
Results. Vitamin D deficiency was detected in 40% of children with neurogenic bladder dysfunctions, a reduced vitamin D level was additionally determined in another 32% of patients, and it was accompanied by secondary hyperparathyroidism in 12%
of cases. Identified violations of calcium and phosphorus metabolism included a decrease in blood calcium levels in 15% of the patients examined.
Conclusion. The presence of correlations between the blood parathyroid hormone level and urine deoxypyridinoline level with the severity of symptoms and some parameters of the quality of life in children with neurogenic urination disorders may indicate the role of the revealed changes in the development of neurogenic urination disorders.
About the Autors
Dmitry Y. Latyshev – PhD in Medical Sciences, Associate Professor at the Department of Propaedeutics of Childhood Diseases, Altai State Medical University; Barnaul, Russia. Е-mail: ldy2014@mail.ru
Yuri F. Lobanov – Doctor of Medical Sciences, Professor, Head of the Department of Propaedeutics of Childhood Diseases, Altai State Medical University; Barnaul, Russia. Е-mail: luf@list.ru
Yakov F. Zverev – Doctor of Medical Sciences, Professor at the Department of Pharmacology, Altai State Medical University; Barnaul, Russia. Е-mail: zver@asmu.ru
Natalia M. Mikheeva – PhD in Medical Sciences, Associate Professor at the Department of Propaedeutics of Childhood Diseases, Altai State Medical University;
Barnaul, Russia. Е-mail: micheeva.1974@mail.ru
Nadezhda A. Tekutyeva – Teaching Assistant at the Department of Propaedeutics of Childhood Diseases, Altai State Medical University; Barnaul, Russia. Е-mail: tekuteva.n@mail.ru
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