Kidney damage in the newcoronavirus disease COVID-19
G.G. Gromova, L.N. Verizhnikova, N.V. Zhbanova, A.V. Stepovaya, I.A. Tyurina
1) Medical Institute, Surgut State University, Surgut, Russia;
2) Surgut Regional Clinical Hospital, Surgut, Russia;
3) Tyumen State Medical University, Tyumen, Russia
Objective. Analysis of the kidney damage in COVID-19 patients in Surgut.
Material and methods. A retrospective cohort clinical study of kidney damage in a new coronavirus infection was carried out; study included 136 patients treated at the Surgut Regional Clinical Hospital from 24.06.2020 to 24.07.2020.
Results and conclusion. Changes in urinanalysis were registered in 70.9% of patients: proteinuria without edema and hypoalbuminemia – in 76.8% (73 patients). A transient increase in creatinine levels without the development of acute kidney injury (AKI) was detected in 16.4% (22 patients) of patients with coronaviral disease. AKI was diagnosed in 17.6% (24) patients. The mean glomerular filtration rate according to the CKD-EPI formula in the AKI group was 46.9 ml/min. In patients with a new coronavirus infection no associations of the incidence of AKI with gender, age, severity of coronavirus infection and a certain class of comorbidity were found. Negative dynamics according to computed tomography data in AKI patients was observed in 54% of cases. In 91.8%, the results of calculating concentration indices made it possible to regard AKI as prerenal.
About the Autors
Galina G. Gromova – Nephrologist, Cand.Sci.(Med.), Senior Lecturer at the Department of Multidisciplinary Clinical Training of the Medical Institute, Surgut State University, Surgut; e-mail: firstname.lastname@example.org, email@example.com.
Natalya V. Zhbanova – Nephrologist, Surgut Regional Clinical Hospital, Surgut; e-mail: firstname.lastname@example.org, email@example.com.
Lyudmila N. Verizhnikova – Therapist, Senior Lecturer, Department of Internal Diseases, Medical Institute, Surgut State University, Surgut; e-mail: firstname.lastname@example.org,
Irina A. Tyurina – Cand.Sci. (Med.), Associate Professor at the Department of Pathophysiology and General Pathology of the Medical Institute, Surgut State University, Surgut; e-mail: email@example.com, firstname.lastname@example.org.
Aurika V, Stepovaya – Therapist, Cand.Sci. (Med.), Associate Professor at the Department of Psychiatry and Narcology, Tyumen State Medical University, Tyumen;
e-mail: email@example.com, firstname.lastname@example.org.