Glomerulonephritis in patients with previous coronavirus infection. Risks and consequences


DOI: https://dx.doi.org/10.18565/nephrology.2024.3.57-60

Polovikov I.P., Zakharova V.L., Sizova Zh.M., Lapidus N.I., Shoikhet D.A., Lenkova N.I.

1) N.F.Sklifosovsky Institute of Clinical Medicine, Sechenov University, Moscow, Russia; 2) Department of Medical and Social Expertise, Emergency and Outpatient Therapy, Institute of Postgraduate Education, Sechenov University, Moscow, Russia; 3) Department of Microbiology, Virology and Immunology, Medical Faculty, Sechenov University, Moscow, Russia; 4) Department of Clinical Pharmacology and Propaedeutics of Internal Diseases, Sechenov University, Moscow, Russia
Glomerulonephritis (GN) is a group of autoimmune inflammatory diseases that occur in the glomeruli of the kidneys and lead to a decrease in nephron function. Currently, the exact cause of GN is unclear, but there are several different putative mechanisms, among which the leading role is given to infectious agents and environmental factors. It is known that group B β-hemolytic streptococcus, human immunodeficiency virus, hepatitis B virus and hepatitis C virus, as well as parvovirus, have a tendency to develop kidney diseases. One of the potential agents may be the SARS-CoV-2 coronavirus, which has a fairly well-studied mechanism of binding to kidney structures and causing acute kidney injury, the central link in the pathogenesis of which is GN. In this article, the pathophysiological mechanisms of GN occurrence, possible ways of GN development associated with coronavirus infection are discussed, and possible medium- and long-term consequences for the corresponding patients are described. This article is written in the format of a literature review.
Keywords: COVID-19, coronavirus infection, kidney injury, glomerulonephritis
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About the Autors

Ivan P. Polovikov – Student, N.V. Sklifosovsky Institute of Clinical Medicine, Sechenov University, Moscow; tel.: +7 (905) 739-51-35;
e-mail: polovikov_i_p@staff.sechenov.ru. ORCID: 0000-0002-3129-9397.
Valeria L. Zakharova – Cand.Sci.(Med.), Associate Professor at the Department of Medical and Social Expertise, Emergency and Outpatient Therapy,
Institute of Postgraduate Education, Sechenov University, Moscow; tel.: +7 (903) 545-93- 83; e-mail: zakharova_v_l@staff.sechenov.ru. ORCID: 0000-0001-5407-6906.
Zhanna M. Sizova – Dr.Sci.(Med.), Professor, Head of the Department of Medical and Social Expertise, Emergency and Outpatient Therapy, Institute of Postgraduate Education, Sechenov University, Moscow; e-mail: sizova_zh_m@staff.sechenov.ru. ORCID: 0000-0002-1242-7074.
Natalia I. Lapidus – Cand.Sci.(Med.), Associate Professor at the Department of Medical and Social Expertise, Emergency and Outpatient Therapy, Institute of Postgraduate Education, Sechenov University, Moscow; e-mail: lapidus_n_i@staff.sechenov.ru. ORCID: 0000-0002-2222-836X.
Denis A. Shoikhet – Teaching Assistant, Department of Microbiology, Virology and Immunology, Medical and Social Expertise, Sechenov University, Moscow;
e-mail: shoykhet_d_a@staff.sechenov.ru. ORCID: 0009-0005-0420-446X.
Nadezhda I. Lenkova – Associate Professor at the Department of Clinical Pharmacology and Propaedeutics of Internal Diseases, Sechenov University, Moscow;
e-mail: lenkova_n_i@staff.sechenov.ru.


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