Русский
Gender differences in kidney function in COVID-19
DOI: https://dx.doi.org/10.18565/nephrology.2025.1.18-21
Perepelitsa S.A.
Imannuel Kant Baltic Federal University, Kaliningrad, Russia
Objective. Identification of gender differences in the kidney function in patients with COVID-19.
Material and methods. The study included 504 patients who were treated for the diagnosis of «Novel coronavirus infection caused by the SARS-CoV-2 virus». Patients were divided into two groups by gender: group A – 311 women, the mean age was 63.1±15.3 years, body mass index (BMI) – 28.8±6.1 kg/m2; group B – 193 men, the mean age was 58.3±15.9 years, BMI – 27.8±5.8 kg/m2. Blood serum creatinine levels were determined, the glomerular filtration rate (GFR) was calculated.
Results. On admission, 68.8% of women and 53.8% of men had signs of renal dysfunction, since the GFR was reduced; by the 7th day, renal function had not returned to normal in 33.6% of women and 43.1% of men, since the GFR remained reduced.
Conclusion. The course of COVID-19 has gender differences, which must be taken into account in clinical practice.
Material and methods. The study included 504 patients who were treated for the diagnosis of «Novel coronavirus infection caused by the SARS-CoV-2 virus». Patients were divided into two groups by gender: group A – 311 women, the mean age was 63.1±15.3 years, body mass index (BMI) – 28.8±6.1 kg/m2; group B – 193 men, the mean age was 58.3±15.9 years, BMI – 27.8±5.8 kg/m2. Blood serum creatinine levels were determined, the glomerular filtration rate (GFR) was calculated.
Results. On admission, 68.8% of women and 53.8% of men had signs of renal dysfunction, since the GFR was reduced; by the 7th day, renal function had not returned to normal in 33.6% of women and 43.1% of men, since the GFR remained reduced.
Conclusion. The course of COVID-19 has gender differences, which must be taken into account in clinical practice.
About the Autors
Svetlana A. Perepelitsa – Dr. Sci. (Med.), Head of the Department of Surgical Disciplines of the Educational Scientific Cluster «Institute of Medicine and Life Sciences»,
Immanuel Kant Baltic Federal University. Address: 14 A.Nevsky str., Kaliningrad, 236041; e-mail: sveta_perepeliza@mail.ru. ORCID: 0000-0002-4535-9805.
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