Use of the anolit in the prevention of peritoneal dialysis catheter-associated infections


DOI: https://dx.doi.org/10.18565/nephrology.2024.4.33-37

Berdinsky V.A., Kotenko O.N., Frolova N.F., Kargalskaya I.G., Ushakova A.I., Orlova A.D., Kozlov I.V., Suvorov O.A.

1) Moscow City Scientific and Practical Center for Nephrology and Transplanted Kidney Pathology, City Clinical Hospital No. 52 of the Moscow Healthcare Department, Moscow, Russia; 2) Pirogov Russian National Research Medical University, Moscow, Russia; 3) Russian University of Medicine, Moscow, Russia; 4) OOO «Vitold Bakhir Institute of Electromechanical Systems and Technologies», Moscow, Russia; 5) Russian Biotechnology University (ROSBIOTECH), Moscow, Russia
Objective. Evaluation of the effectiveness of the antiseptic drug Anolit neutral in the prevention of catheter exit site infection, tunnel infection and dialysis peritonitis.
Material and methods. A prospective study lasting 12 months based on the Peritoneal Dialysis Department of the City Clinical Hospital No. 52 of the Moscow Health Department. Of the 88 patients receiving outpatient peritoneal dialysis, 47 used Anolit neutral for hand and catheter exit site treatment, while another group of 41 patients used chlorhexidine bigluconate 0.05%.
Results. The incidence of catheter exit site infection did not differ in both groups. The incidence of dialysis peritonitis was generally less frequent in the Anolit neutral group compared to the chlorhexidine group, but was not statistically significant. The incidence of peritoneal dialysis catheter removal was similar in both groups. Skin erythema developed in only two patients using Anolit neutral.
Conclusion. The data obtained suggest that Anolit neutral may be used as an alternative to prevent catheter exit site infection, tunnel infection, and dialysis peritonitis.

About the Autors


Vitaly A. Berdinsky – Head of the Nephrology Department No. 4, City Clinical Hospital No. 52, Moscow Healthcare Department. Moscow. Address: 3 Pekhotnaya St., Moscow, 123182; e-mail: vitaly.berdinsky@yandex.ru. ORSID: https://orcid.org/0000-0001-7407-5695
Oleg N. Kotenko – Dr.Sci. (Med.), Chief External Expert in Nephrology, Head of the Moscow City Scientific and Practical Center for Nephrology and Transplanted Kidney Pathology, City Clinical Hospital No. 52 of the Moscow Healthcare Department, Professor at the Department of General Therapy, Faculty of Continuous Professional Education, Pirogov Russian National Research Medical University. Address: 3 Pekhotnaya St., Moscow, 123182; e-mail: olkotenko@yandex.ru. ORCID: https://orcid.org/0000-0001-8264-7374
Nadiya F. Frolova – Dr.Sci. (Med.), Deputy Chief Physician for Nephrology, City Clinical Hospital No. 52, Moscow Healthcare Department, Associate Professor at the Department of Nephrology, Faculty of Continuous Professional Education, Russian University of Medicine. Address: 3 Pekhotnaya St., Moscow, 123182; e-mail: nadiya.frolova@yandex.ru. ORCID: http://orcid.org/0000-0002-6086-5220
Irina G. Kargalskaya – Head of the Telenephrology Center project, City Clinical Hospital No. 52, Moscow Healthcare Department, Head of the Patient-Oriented Telemedicine Committee at the All-Russian Union of Patients. Address: 3 Pekhotnaya St., Moscow, 123182; e-mail: info@longavitapro.com. ORCID: https://orcid.org/0009-0006-6261-0607
Anzhela I. Ushakova – Head of the Hemodialysis Department, City Clinical Hospital No. 52, Moscow Healthcare Department. Address: 3 Pekhotnaya St., Moscow, 123182; e-mail: anzhela_52@inbox.ru. ORCID: https://orcid.org/0000-0002-3959-6281
Alena D. Orlova – Nephrologist, Hemodialysis Department, City Clinical Hospital No. 52, City Clinical Hospital No. 52, Moscow Healthcare Department. Address: 3 Pekhotnaya St., Moscow, 123182; e-mail: DOC.alena.orlova@mail.ru. ORCID: https://orcid.org/0009-0000-5428-3649
Igor V. Kozlov – Cand.Sci. (Tech.), Chief Technologist, OOO “Vitold Bakhir Institute of Electromechanical Systems and Technologies”. Address: Bldg. 3, 34 Narodnogo Opolcheniya St., Moscow, 123423; e-mail: ph.d.kiv@mail.ru
Oleg A. Suvorov – Dr.Sci. (Tech.), Professor oatf the Department of Food Industry, Hotel Business and Service, Russian Biotechnology University (ROSBIOTECH).
Address: 11 Volokolamskoe Shosse, Moscow, 125080; e-mail: SuvorovOA@yandex.ru. ORCID: https://orcid.org/0000-0003-2100-0918


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