S.V. Moiseev, MD, PhD, Prof; G.P. Arutyunov, MD, PhD, Prof; V.V. Fomin, MD, PhD
IM Sechenov Moscow Medical Academy, Russian State Medical University
ACE inhibitors slow irreversible worsening of renal function in chronic kidney disease with proteinuria, that is due not only to their blood pressure lowering effect, but also to their ability to reduce proteinuria. The reference prove of ACE inhibitors nephroprotective action was shown in trials REIN and AASK, in which ramipril was used.