Aim. Optimization ot the approaches to diagnosis of chronic kidney disease (CKD) in teenagers in ambulatory practice.
Methods. 2000 teenagers age 15 – 21 years (mean 16,8+1,3 years) undergone ambulatory screening for microalbuminuria by Micral-test. In those, who had persistent (>6 months) microalbuminuria, body mass index (BMI) was assessed, biochemical blood tests, blood pressure monitoring, ultrasound kidney scanning were performed, glomerular filtration rate (GFR) was determined.
Results. 145 patients had persistent microalbuminuria. 53,8% had normal GFR, 44,1% had GFR 60-89 ml/min/1,73m2, 2,1% had GFR <60ml/min/1,73m2. Only 10 (12,8%) teenagers with normal GFR had conditions, associated with microalbuminuria. 28,1% with GFR microalbuminuria had conditions, associated with microalbuminuria (c2=5,2; р=0,026 ws group with normal GFR). 40,5% teenagers with normal GFR and 61% with GFR 60-89 ml/min/1,73m2 had ultrasound signs of kidney disease (c2 =7,11; р=0,008). Teenagers with isolated diastolic arterial hypertension had higher albuminuria and more often demostrated ultrasound signs of kidney involvment, than teenagers with systolic arterial hypertension.
Сonclusion. In ambulatory practice detemination of albuminuria, glomerular filtration rate and ultrasound scanning can be used for chronic kidney disease diagnosis.

Keywords: teenagers, microalbuminuria, chronic kidney disease