Patients receiving renal replacement therapy with hemodialysis and taking NSAIDS: real clinical practice


DOI: https://dx.doi.org/10.18565/nephrology.2021.4.43-47

A.P. Rebrov, E.V. Grigoryeva, G.S. Petrov, J.I. Vorobieva, M.S. Sitnikova

1) Saratov State Medical University named after V.I. Razumovsky, Ministry of Health of Russian Federation, Department of the Internal Medicine, Saratov, Russian Federation; 2) GUZ “Regional Clinical Hospital”, Saratov, Russian Federation
Objective. To study the features of the use nonsteroidal anti-inflammatory drugs (NSAIDs) in patients receiving programmed hemodialysis.
Material and methods. A survey of 200 patients receiving programmed hemodialysis was performed.
Results. The majority of patients: 162 (81%) took NSAIDs within the previous 6 months, and 91 (56.2%) patients took NSAIDs during the last month, of which 64 (70.3%) took the drugs more often than 2 times in Week. The main reasons for taking NSAIDs are headache, joint and muscle pain. The majority of patients took on their own non-selective NSAIDs, 108 (54%) patients did not know about the risks of undesirable effects when taking NSAIDs.
Conclusion. Most patients receiving renal replacement therapy with hemodialysis often and long-term use NSAIDs. Considering the need to use anticoagulants during the hemodialysis procedure, the age of the patients, the presence of comorbid conditions, the use of NSAIDs in this category of patients is associated with a high risk of complications. In this regard, it is necessary to clarify the intake of drugs by patients, to inform patients in a timely manner about possible complications while taking NSAIDs, to recommend the safest drugs and schemes for their use.

About the Autors


Rebrov Andrey P. – MD, professor, head of hospital therapy department of Federal State Educational Institution of High Education “Saratov State Medical University n.a. V.I. Razumovsky” Ministry of Health Russian Federation. Address: 410012, Saratov, 112 Bolshaya Kazachya Str.; e-mail: andreyrebrov@yandex.ru; ORCID:
https://orcid.org/0000-0002-3463-7734.
Grigoryeva Elena V. – PhD, assistant of professor of hospital therapy department of Federal State Educational Institution of High Education Saratov State Medical University n.a. V.I. Razumovsky Ministry of Health Russian Federation; Address: 410012, Saratov, 112 Bolshaya Kazachya Str.; e-mail: lek133@yandex.ru;
ORCID: https://orcid.org/0000-0001-6064-560X.
Petrov Gennady S. – nephrologist, GUZ "Regional Clinical Hospital". Address: 410053, Saratov, Smirnovskoe gorge str., 1B; e-mail: petrovgs2007@yandex.ru; ORCHID: https://orcid.org/0000-0003-2312-5271.
Vorobieva Julia I. – resident of hospital therapy department of Federal State Educational Institution of High Education Saratov State Medical University n.a. V.I. Razumovsky Ministry of Health Russian Federation; Address: 410012, Saratov, 112 Bolshaya Kazachya Str.; e-mail: miss.yulya-vorob@yandex.ru; ORCID: https://orcid.org/0000-0002-1912-173X.
Sitnikova Marina S. – resident of hospital therapy department of Federal State Educational Institution of High Education Saratov State Medical University n.a. V.I. Razumovsky Ministry of Health Russian Federation; Address: 410012, Saratov, 112 Bolshaya Kazachya Str.; e-mail: marina_sitnikova_93@bk.ru; ORCID: https://orcid.org/0000-0003-3880-9596.


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