Русский
The prevalence of sarcopenia in patients with chronic heart failure and chronic kidney disease
DOI: https://dx.doi.org/10.18565/nephrology.2023.3.18-23
Sokolova A.V., Dragunov D.O., Arutyunov G.P.
1) Pirogov Russian National Research Medical, Moscow, Russia; 2) Research Institute of Healthcare Organization and Medical Management of the Moscow Healthcare Department, Moscow, Russia
Materials and methods. The analysis included 107 patients with an established diagnosis of CHF, mean age was 69.6±11.3 years. All patients underwent screening for sarcopenia and CKD in accordance with the recommendations. For statistical analysis of the obtained data, the R language and RStudio software were used.
Results. CKD was detected in 105 patients with CHF: 32 patients had C2, 31 patients had C3a, 32 patients had C3b, 4 patients had C4 (CKD4), and only 2 patients did not have CKD. The largest number of CHF decompensation was detected in patients with CKD3b and CKD4. Presarcopenia was detected in 39% of patients with CHF and CKD, and sarcopenia in 38%. According to multivariate regression analysis, the risk of sarcopenia was most influenced by fat mass OR 1.14, 95% CI [1.01;1.34], P=0.057, muscle mass index OR 0.61, 95% CI [0.42 ;0.79], P=0.002 and male gender OR 1.17, 95% CI [60.9;85.77], P<0.001.
Conclusion. In patients with CHF and CKD, the increase in sarcopenia occurs as the filtration function of the kidneys decreases.
About the Autors
Anna V. Sokolova – Cand.Sci. (Med.), Associate Professor, Associate Professor at the Department of Propaedeutics of Internal Diseases, Faculty of Pediatrics, Pirogov Russian National Research Medical University, Leading Specialist at the Organizational and Methodological Department for Therapy, Research Institute of Healthcare Organization and Medical Management of the Moscow Healthcare Department. Address: 4 Startovaya st., Moscow
Dmitry O. Dragunov – Cand.Sci. (Med.), Associate Professor, Associate Professor at the Department of Propaedeutics of Internal Diseases, Faculty of Pediatrics, Pirogov Russian National Research Medical University, Head of the Organizational and Methodological Department for Therapy, Research Institute of Healthcare Organization and Medical Management of the Moscow Healthcare Department. Address: 4 Startovaya st., Moscow
Grigory P. Arutyunov – Dr.Sci. (Med.), Professor, Corresponding Member of RAS, Head of the Department of Propaedeutics of Internal Diseases, Faculty of Pediatrics, Pirogov Russian National Research Medical University. Address: 4 Startovaya st., Moscow
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