Multifactorial kidney damage in a comorbid patient


DOI: https://dx.doi.org/10.18565/nephrology.2024.4.45-47

Yumasheva V.A., Komarova I.S., Rachina S.A., Mayorov V.V., Melnik D.M., Mirzakhamidova S.S.

1) Sechenov University, Moscow, Russia; 2) S.S. Yudin City Clinical Hospital, Moscow, Russia
Chronic kidney disease (CKD) is associated with severe comorbidity of a wide range of mental and physical conditions. The presence of concomitant pathologies aggravates the course of the underlying disease and contributes to the progression of kidney damage. The article presents a clinical description of a comorbid 80-year-old female patient with multifactorial renal damage due to arterial hypertension, viral hepatitis C, purine metabolism disorders, and markers of autoimmune damage based on the results of serological and intravital pathological examination. The mechanisms of complex renal damage and the importance of influencing them to maintain an optimal quality of life in a comorbid patient are discussed.
Keywords: renal damage, comorbidity, nephrosclerosis, chronic kidney disease, quality of life
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About the Autors

Valentina A. Yumasheva – 6th-Year Student, Sechenov University. Address: Bldg. 2, 8 Trubetskaya St., Moscow, 119992; Tel.: 8 (916) 043-34-19;
E-mail: valentina-jumasheva@rambler.ru. ORCID: https://orcid.org/0000-0002-4388-5609.
Irina S. Komarova – Cand.Sci. (Med.), Associate Professor, Department of Hospital Therapy No. 2, Sechenov University. Address: Bldg. 2, 8 Trubetskaya St., Moscow, 119992; Tel.: 8 (926) 113-43-41; E-mail: plaksuchka@rambler.ru. ORCID: https://orcid.org/0000-0001-6425-0621.
Svetlana A. Rachina – Dr.Sci. (Med.), Head of the Department of Hospital Therapy No. 2, Sechenov University. Address: Bldg. 2, 8 Trubetskaya St., Moscow, 119992;
tel.: 8 (910) 715-89-55, e-mail: Stchina@avetlana.Rantibiotic.ru. ORCID: https://orcid.org/0000-0002-3329-7846.
Vasily V. Mayorov– Nephrologist, City Clinical Hospital named after S.S. Yudin. Address: 4 Kolomensky proezd, Moscow, Russia, 115446; tel.: 8 (916) 887-22-97;
e-mail: Vasso88-88@bk.ru. ORCID: https://orcid.org/0000-0001-5094-1261.
Dmitry M. Melnik – Nephrologist, City Clinical Hospital named after S.S. Yudin. Address: 4 Kolomensky proezd, Moscow, Russia, 115446; tel.: 89103154991,
e-mail: melnik.nephro@gmail.com. ORCID: https://orcid.org/0009-0006-3144-7165.
Svetlana S. Mirzakhamidova – Cand.Sci. (Med.), Deputy Chief Physician for Medical Work, City Clinical Hospital named after S.S. Yudin. Address: 4 Kolomensky proezd, Moscow, Russia, 115446; tel.: 8 (916) 206-33-08; e-mail: rimatevs@mail.ru. ORCID: https://orcid.org/0000-0002-5807-5027.


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