Patients receiving renal replacement therapy with hemodialysis and taking NSAIDs during the COVID-19 pandemic


DOI: https://dx.doi.org/10.18565/nephrology.2022.3.20-24

Rebrov A.P., Grigoryeva E.V., Petrov G.S., Polidanov M.A., Kondrashkin I.E., Blokhin I.S., Tyapkina D.A., Boroday A.A.

Saratov State Medical University named after V.I. Razumovsky, Ministry of Health of Russian Federation, Department of the Internal Medicine, Saratov, Russia
Objective. To study the features of the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in patients receiving programmed hemodialysis (HD) during the COVID-19 pandemic.
Material and methods. A survey of 196 patients HD was performed.
Results. More than half of the patients (110/56%) receiving program HD took NSAIDs during the previous 6 months, 75.5% patients took NSAIDs during the last month, of which 27.7% took medications daily. The main reasons for taking NSAIDs are joint pain, headache. Almost half of the patients (47%) had a new coronavirus infection (NCI), of which 58.7% patients regularly took NSAIDs, and 28.2% patients – daily during the last month; 53.8% patients among the patients who did not undergo NICI regularly took NSAIDs, and (27.3% - daily during the last month.
Conclusion. More than half (56%) of patients receiving program HD often and for a long time take NSAIDs, despite the use of anticoagulants during hemodialysis. There was a slight increase in the frequency of NSAID intake in patients with COVID-19 infection. Considering the fact that the use of NSAIDs in this category of patients is associated with a high risk of complications, the urgent task remains to timely clarify the fact of the patient's use of NSAIDs, correction of therapy, selection of the safest drugs and their use regimens.

About the Autors


Rebrov Andrey P. – MD, professor, head of hospital therapy department of Federal State Educational Institution of High Education Saratov State Medical University n.a. V.I. Razumovsky Ministry of Health Russian Federation. Address: 410012 Saratov, 112 Bolshaya Kazachya Str.; tel.: +7 (845) 249-14-37; e-mail: andreyrebrov@yandex.ru.
ORCID: https://orcid.org/0000-0002-3463-7734.
Grigoryeva Elena V. – PhD, assistant of professor of hospital therapy department of Federal State Educational Institution of High Education Saratov State Medical University n.a.
V.I. Razumovsky Ministry of Health Russian Federation. Address: 410012 Saratov, 112 Bolshaya Kazachya Str.; tel.: +7 (845) 249-14-37; e-mail: lek133@yandex.ru. ORCID: https://orcid.org/0000-0001-6064-560X.
Petrov Gennady S. – assistant of hospital therapy department of Federal State Educational Institution of High Education Saratov State Medical University n.a. V.I. Razumovsky Ministry of Health Russian Federation. Address: 410012 Saratov, 112 Bolshaya Kazachya Str.; tel.: +7 (845) 249-14-37; e-mail: petrovgs2007@yandex.ru.
ORCID: https://orcid.org/0000-0003-2312-5271.
Polidanov Maxim A. – student, Saratov State Medical University named after V.I. Razumovsky Ministry of Health of Russian Federation. Address: 410012 Saratov, 112 Bolshaya Kazachya Str.; tel.: +7 (845) 249-14-37; e-mail: maksim.polidanoff@yandex.ru.
ORCID: https://orcid.org/0000-0001-7538-7412.
Kondrashkin Ivan E. – student, Saratov State Medical University named after V.I. Razumovsky Ministry of Health of Russian Federation. Address: 410012 Saratov, 112 Bolshaya Kazachya Str.; tel.: +7 (845) 249-14-37, 7 (845) 249-14-37; e-mail: ivan.kondrashckin@yandex.ru.
ORCID: https://orcid.org/0000-0001-8827-8143.
Blokhin Igor S. – student, Saratov State Medical University named after V.I. Razumovsky Ministry of Health of Russian Federation. Address: 410012 Saratov, 112 Bolshaya Kazachya Str.; tel.: +7 (845) 249-14-37; e-mail: ig.bloxin2010@yandex.ru.
ORCID: https://orcid.org/0000-0003-3224-6913.
Tyapkina Darya A. – student, Saratov State Medical University named after V.I. Razumovsky Ministry of Health of Russian Federation. Address: 410012 Saratov, 112 Bolshaya Kazachya Str.; tel.: +7 (845) 249-14-37; e-mail: orchidaceae.2017@yandex.ru.
ORCID: https://orcid.org/0000-0001-7886-1175.
Boroday Alexandra A. – student, Saratov State Medical University named after V.I. Razumovsky Ministry of Health of Russian Federation. Address: 410012 Saratov, 112 Bolshaya Kazachya Str.; tel.: +7 (845) 249-14-37; e-mail: alexandra.108@mail.ru.
ORCID: https://orcid.org/0000-0002-6632-5110.


Similar Articles


Бионика Медиа