Arterial hypertension and chronic renal failure in patients on long-term ambulatory management


L.A. Alekseeva, L.A. Popova, I.V. Ryzhenkova

Purpose. Evaluation of the prevalence and prognostic significance of essential arterial hypertension (EAH) in patients with chronic renal failure with long-term follow-up in a large multidisciplinary outpatient medical facility. Materials and methods. The medical records of 175 patients (144 men and 31 women) aged 32 to 95 years (mean age, 78.6 years) with chronic renal insufficiency (glomerular filtration rate (GFR) <50 ml/min) were retrospectively analyzed. Maximum duration of follow-up was 30 years. Biochemical blood parameters, including creatinemia, and changes in urine were examined. Imaging survey methods were used as appropriate. Etiology of CRF was especially defined in all patients. Results. The presence of EAH with different degrees of reduction of glomerular filtration rate was associated with a significant increase in the frequency of complicated forms of coronary artery disease, atrial fibrillation, as well as diabetic nephropathy, urate nephropathy, and ischemic kidney disease. Conclusion. EAH is assosiated with increased risk of cardiovascular complications in patients with chronic renal failure that determines the need for optimizing antihypertensive therapy on an outpatient phase.

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